| Department of Internal Medicine/Diabetes and Endocrinology, University Hospital of Lund, Sweden
Insulin pens dribble from the tip of the needle after injection.
Aim.
To study different insulin pens regarding leakage from the tip of the needle after injection.
Patients and method.
Six pens were tested; Saline Pen 3.0 ml (Lilly), B-D Pen 3.0 ml, NovoLet 1.5 and 3.0 ml, NovoPen 1.5 and 3.0 ml. Twenty volunteers were injected with sterile saline and the needle was withdrawn after 1, 3, 5, or 7 s respectively. Any dribble was collected on a filter paper and weighed. The procedure was videotaped.
Results.
There was a minimum of dribbling from the 1.5 ml pens. Eight out of 20 NovoPen 3.0 ml and B-D Pen 3.0 ml, 16 out of 20 NovoLet 3.0 ml, and 19 out of 20 Saline Pen (Lilly) dribbled after a 7 s hold-in time. The 8 B-D Pen 3.0 ml had leaked 4.0 mg (2.4-18.8), the 8 NovoPen 3.0 ml 4.7 mg (3.8-6.7), the 16 NovoLet 3.0 ml 5.0 mg (3.1-16.6) and the 19 Saline Pen 3.0 ml had leaked 9.2 mg (4.9-19.1).
Conclusion.
There is a clinically significant leakage of fluid from the needle tip even after 7 s hold-in time. Patients should be taught to hold the needle in for at least 10 s to be assured they get the intended dose. Copyright © 2000 John Wiley & Sons, Ltd.
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