Thèmes : diabetes glucose, glucose, hypoglycemie, centre information

	Accueil > Sitemap > Centre d'information > Références Medicales : Hypoglycémie > Verny C., Remy C., Sachon C., Bosquet F., Casanova S., Grimaldi A. : Nocturnal hypoglycemia in insulin-dependent diabetics. Verny C., Remy C., Sachon C., Bosquet F., Casanova S., Grimaldi A. : Nocturnal hypoglycemia in insulin-dependent diabetics.   Back Service de Diabetologie-Metabolisme, Hopital de la Pitie, Paris. [Article in French] Nocturnal hypoglycemia in insulin-dependent diabetics. OBJECTIVES: Repeated hypoglycaemia has been reported to impair recognition of subsequent hypoglycaemia with a high risk of severe hypoglycaemia. This intensified insulin therapy may be dangerous in insulin-dependent diabetes mellitus (IDDM) patients with unawareness of hypoglycaemia. METHODS: We assessed the incidence of nocturnal hypoglycaemia and the benefit of an additional bedtime snack in IDDM patients treated by 2 or 3 daily injections. Capillary blood glucose was measured by finger strip at 10 p.m. and plasma venous glycaemia was determined at 0, 2, 4 and 8 a.m. RESULTS: The study was composed of two phases. In the first phase, patients (n = 93) did not receive any snack at bedtime. Blood glucose fell to 2.75 mmol/l or less in 33%. Among the 40 patients with a 10 p.m. glycaemia of 9 mmol/l or less, 57.5% experienced nocturnal hypoglycaemia vs 15% of the 53 others. The second phase concerned 106 IDD patients. An additional bedtime snack was given when 10 p.m. blood glucose was 9 mmol/l or less. The incidence of hypoglycaemia fell to 32% (14 of 44 IDDM) i.e. a significant benefit of 44% (p < 0.01). However patients who received this additional bedtime snack had a slightly higher 8 a.m. glycaemia than those with 10 p.m. glycaemia at 9 mmol/l or less during the first phase (9.61 +/- 5.67 mmol/l vs 7.75 +/- 4.30 mmol/l) but this result is not significant. CONCLUSION: Prevention of nocturnal hypoglycaemia may be achieved in IDDM patients by bedtime glucose determination and an additional snack when glycaemia is 9 mmol/l or less.. If you would like to obtain the full article in French, please contact the publisher: Masson-Periodiques at the following phone number: +33 1 40 46 62 00.
Trucs & astuces pour les ados diabétiques, L'école Moi aussi je suis diabétique (jusqu'à 12 ans), Qu'est-ce qu'une hypo? Le prélèvement capillaire, Jones P.M. : Use of a course on self-control behavior techniques to increase adherence to prescribed frequency for self-monitoring blood glucose. Hypoglycémie, Fahey P.J., Stallkamp E.T., Kwatra S. : The athlete with type I diabetes: managing insulin, diet and exercise. Hypoglycémie, Beregszaszi M., Tubiana-Rufi N., Benali K., Noel M., Bloch J., Czernichow P. : Nocturnal hypoglycaemia in children and adolescents with insulin-dependent diabetes mellitus: prevalence risk factors. BD Diagnostic Systems Contrôler sa glycémie, Reporter les résultats Données personelles
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